RESEARCH  

 

DEPARTMENT OF ORAL PATHOLOGY & MICROBIOLOGY

 
   

1) List of Dissertations:

 
   

Sl No

Year

Title

1

1993

Histopathological study of apparently normal buccal mucosa in lepramatous leprosy

2

1993

Histopathological analysis of leukoplakia.

3

1994

Quantitative analysis of human buccal epithelium in iron deficiency anemia

4

1995

Effect of smoking on the prevalance & intraoral distribution of candida albicans.

5

1995

Histological alteration associated with the use of smokeless tobacco in apparently normal buccal mucosa.

6

1996

Jaw bone lesions-radiological & histological corelations.

7

1996

Langerhans cell in normal buccal mucosa, leucoplakia & squamous cell carcinoma.

8

1997

Silver stained nucleolar organising regions in salivary gland tumors- A quantitative analysis.

9

1997

An in-vitro comparison of cariogenecity of sugar & aspartame

10

1998(Feb)

Role of Folic acid in the pathogenesis of oral submucous fibrosis- A Co-etiologic factor (A case control study).

11

1998(Feb)

A role of laminin-“an adhesion-receptor interphase molecule”in pathogenesis of lichenplanus.-An immunohistochemical study.

12

1998(Sept)

Pericoronitis associated with mandibular third molar- A microbial study.

13

1998(Sept)

A study of apparently normal buccal mucosa in smokers–A clinicopathological examination.

14

1998(Sept)

Morphometric analysis of silver stained nucleolar organising regions in Odontogenic cysts & Odontogenic tumours.

15

1999(Feb)

Cemental incremental lines in humans as a criteria for age estimation.

16

1999(Sept)

A study of histological evaluation of leucoplakia for the superimposition of candida.

17

1999(Sept)

Efficacy of various chemicals for decalcification of dental hard tissues.

18

1999(Sept)

Study of pulp mineralisations in human teeth.

19

1999(Sept)

Observer variability in histologic grading in leukoplakia.

20

2000

Evaluation of fungal infections in HIV positive patients.

21

2000

Detection of anti HIV antibodies in saliva by ELISA.

22

2000

Immunohistochemical detection of desmosomes in oral squamous cell carcinomas, correlation with differentiation mode of invasion and metastatic potential.

23

2000

Identification, quantitative assessment and comparison of bacteria isolated from infected root canals of decayed teeth association with clinical and radiographic findings.

24

2001

The role of lasers and transforming growth factor beta in healing human extraction sockets invivo study.

25

2001

A genetic study: Hereditary pattern in ectodermal dysplasia: Affected/unaffected members.

26

2001

Histochemical evaluation of drug induced and inflammatory gingival enlargement.

27

2001

Cytomorphometric analysis of squames obtained from normal oral mucosa, iron deficiency anemia and speckled leukoplakia by exfoliative cytology.

28

2002

Saliva- An epidemiological tool for HIV survellance.

29

2002

Cytomorphometric analysis of normal buccal cellc in alcoholics.

30

2002

Root surface caries- An invitro study.

31

2003

Efficacy of drug in OSMF- An histopathologic evaluation.

32

2004

Prospective comparative study of exfoliative cytology with fine needle aspiration cytology and incisional biopsy in clinically suspected oral squamous cell carcinoma patients.

33

2004

PCR- study to evaluate dissemination of cancer cells after incisional biopsy in oral squamous cell carcinoma.

34

2004

Soft tissue  changes in radiographically normal impacted third molars.

35

2005

Pretreatment and post treatment evaluation of mast cell number in oral sub mucous fibrosis.

36

2006

Study of mast cells and tumor angiogenesis in different grades of oral squamous cell carcinoma.

37

2006

Oral carriage of yeasts, coliforms, and staphylococci in patients with clinically and histologically diagnosed oral squamous cell carcinoma correlated with histological grading and TNM staging.

38

2006

Histological evaluation of oral mucosa adjacent to the primary lesion of oral squamous cell carcinoma and from the most suggestive areas after vital staining, to evaluate the possibility of field cancerization.

39

2006

A comparative study of collagen fibers in the odontogenic cysts and odontogenic tumors with picrosirius red stain and Polarizing microscopy.

40

2006

Invitro study of phogocytic function of salivary nutrophils in patients with multiple various lesions

41

2006

 Vital staining with Toludine Blue and Lugol’s Iodene to determine clinical and histopathological changes in oral mucosa of chronic tobacco users.

42

2006

Comparative study of expression of tenascin by immunohisto chemical method, in developing teeth inflammatory gingival hyperflasia and OSCC

43

2007

Comparing superficial and advancing front of SCC using epthlial membrane antigen as marker

44

2007

Estimation of micro nucleus in exfoliated clls from oral mucosa in normal subjects, tobacco users and OSCC

45

2007

Detection of hepatitis b surface antigen and antichepatis C virus antibodirs in oral lichen planus patients and its possible correlation with pathogenisis of Oral luchen planus

46

2007

Clinico pathological study ot evaluate oral lichen planus for the establishment of clinical and  histopathological diagnositic criteria

47

2007

Fibrogen demonstration the oral lichen planus –an unimucoflacroses study

48

2007 ( Sept)

Estimation of Salivary Leukocyte Protease inhibitor and its potential interactions levels in saliva of patients with chronic Periodontitis

49

2007 ( Sept)

Histological grading of dysphasia in tobacco associated leukoplakia: An image cytometric study   
 

50

2007 ( Sept)

Comparing the efficacy of modified Papanicolaou stain with that of Ayoub-shklar and haematoxylin-eosin stain for the demonstration of keratin in paraffin embedded tissue sections-A histochemical study.”     

51

2007 ( Sept)

Comparison and correlation of glucose levels in               serum and saliva of patients with diabetes  mellitus, to establish saliva as a diagnostic  adjunct

 
   

2. Ongoing Dissertations:

 
   

Sl No

Year / Batch

Title

01

2006-09

Determination of levels of salivary IgA subclasses in patients with minor Recurrent Apthous ulcer.

 

02

2006-09

An immunohistochemical study of perlecan expression in epithelial cells of normal oral mucosa, dysplastic lesions lesions and squamous cell carcinoma.”

03

2006-09

Cytomorphometric analysis of exfoliated cells from apparently normal oral mucosa of type II Diabetic patients and non-diabetic individuals.

04

2006-09

“A Retrospective quantitative evaluation of tissue eosinophils and a prospective comparison of tissue eosinophilia with absolute eosinophil count in patients with various grades of oral squamous cell carcinoma using two special stains- Congo red and Giemsa.”

 
   

3. Department Research Work : -

 
   

Sl No

Year

Title

1

1999

Pulp Fixation: Immersion vs. perfusion.
An experimental study.

2

2000

Study of collagen fibers in odontogenic cyst and tumors using picrosirius red and polarizing microscope.

3

2000

Effects of low powered lasers on platelet aggregation.

3

2001

Prevalence of HIV infection in antenatal mothers: A case control study.

4

2001

Dental unit water line controversy: An evolving issue

5

2002

Cross contamination with impression materials and casts

6

2002

Isolation of micro organisms from root canal system

7

2002

Watchman at the immune gate-mast cells

8

2003

Mirror image biopsy

9

2003

Comparative study of phagocytic activity of neutrophils in saliva and blood in smokers and non smokers

10

2003

Palmar Dermatoglyphics in oral squamous cell carcinoma

11

2004

Stromal characterization in oral submucous fibrosis using picrosirius red and polarizing microscope.

12

2004

Epithelial mesenchymal interactions in odontogenic tumors

13

2005

Estimation of salivary glucose levels in patients with diabetes mellitus

14

2005

Innervation in juxta epithelial region in oral lichen planus :A histochemical study

15

2005

Salivary Neurtophil Phagocytic activity in patients with Recurrent Aphtuous Ulcer

16

2005

“Dectection and comparasion of micronuclei in exfoliative cells using feulgen reaction in normal, chronic tobacco abusers and oral carcinomas cases”

17

2005

“Comparative study of expression of tenascin in inflammatory gingival hyperplasia & Normal oral mucosa

18

2006

Differentiation of bone from surrounding soft tissues using methylene blue-Acid fuchsin: A newer stain combination

19

2006

Quantitative analysis of stromal eosinophils & mast cells in Oral Premalignancy and squamous cell carcinoma.

20
2007
Last words of the tissue: I died at…….?
21
2007
Application of pulp to tooth area ratio for age estimation
22
2007
Exfoliative cytology in evaluation of glycaemic status in type II Diabetis Mellitus.
 
   

4. Ongoing Department Research Project:-

 
   

Sl No

Year

Title

1

2003-08

Histopathological evaluation of squamous cell carcinomas to determine the pattern at the invasive front of the tumor by using Epithelial Membrane Antigen (EMA): A Diagnostic discriminant- an immunohistochemical study.

2

2003-08

 Clinical and histopathological evaluation of patients having tobacco habit with or without obvious clinical presentation.

3

2003-08

Comparison of effect of treatment modalities in patients with Oral Sub Mucous Fibrosis.

4

2004-08

Study of intraepithelial expression of Perlecan, a basement membrane- type heparan sulphate proteoglycan as a marker for dysplastic changes of oral epithelium and to establish a co-relation (if any) with the degree of dysplasia.

5

2004-08

Detection of Hepatitis B Surface Antigen And Anti Hepatitis C Virus Antibodies In Oral Lichen Planus Patients And Co-Relation Of Its Possible Role In Pathogenesis Of Oral Lichen Planus

6

2005-09

Comparision & correlation of glucose levels in serum & saliva of patients with Diabetes Mellitus, to establish saliva as a diagnostic adjunct.

7

2004-2007

Pre treatment & post treatment evaluation of mast cell number in oral submucous fibrosis

8

2001-08

Standrdization of saliva for detection of Anti HIV antibody and use of saliva as a co diagnostic modality in known HIV cases, commercial sex workers and anti natal mothers

9

2004-2008

Detection & comparison of micronuclei in exfoliative cells using feulgen reaction in normal, chronic tobacco abusers & OSSC

10

2004-2008

 Vital staining with toluidine blue & lugols iodine to determine clinical and histopathological changes in oral mucosa of chronic tobacco users.